Dental Angels on a Mission
Issa Karkar, DDS:
Practice Profile Page


Dental Angels on a Mission
Issa Geroge Karkar, DDS

San Francisco, CA













A list of major dental treatments which I offer my patients:

Dental cleaning

White fillings


Inlays & onlays


Clear aligners

Porcelain veneers

Teeth whitening

Dentures & partials

Root canal treatment

Tooth extraction

TMJ treatment

Dental implants


Offers Even28 at-home™? No

Offers Even28 at-dentist™? No

Offers Invisalign®? Yes


Monday: 9:00 am to 6:00 pm

Tuesday: 9:00 am to 6:00 pm

Wednesday: 9:00 am to 6:00 pm

Thursday: 9:00 am to 6:00 pm

Friday: 9:00 am to 6:00 pm

Saturday: 9:00 am to 5:00 pm (by appointment only)

Sunday: Closed





Check out what some of our happy patients are saying about us:

Sally D. from Baldwinsville, NY (Source: Yelp)


Saw Dr. Karkar while on vacation in San Francisco for an emergency visit due to a broken tooth. Dental Angels took me in right away. Awesome facility with state of the art equipment, friendly, efficient staff, and excellent dentistry had me back out the door to enjoy the rest of my stay.  Highly recommend!

Eric S. from San Francisco, CA (Source: Yelp)


I have been seeing Dr. Karkar and Dr. Marejo for many years now. Dr. Karkar is a wonderful dentist, very dedicated to his profession, and always concerned to do the best possible job. Even under difficult circumstances, he is kind, considerate, and does his utmost to make sure that the procedure is as pleasant as possible. Dr. Karkar uses the latest available technology to make the work as easy as possible; the new xray machine in the Mission office is fantastic – getting an xray was always one of my least favorite procedures, but this new machine makes everything so much easier. The rest of the staff and doctors are equally good. I can’t say enough good things about Dental Angels.

Sam K. from Burlingame, CA (Source: Yelp)


An absolutely fantastic experience in dentistry the likes of which I have never experienced. I went to this office on the referral of my friend, and I’m so glad i made the appointment. Dr. Karkar is truly one of the finest dentist I’ve ever experienced. I have had so many problem with my teeth and felt like wherever I went previously it took a year and never done right. I frankly gave up on getting implants done. Dr. Karkar and Dr Merejo where able to repair the mistakes of my previous dentist in one visit. I was in so much pain for weeks So on a recommendation i took a chance. Let me tell you, i will never ever let another dentist work on me. He was so gentle,he explained what needed to be done and my goodness. Polite, professional, and truly artistic int the work he did on me. I’m gong back to finish all my teeth. I cant wait. I highly , highly , highly recommend this office and Dr. Karkar  i wish i could give 10 stars. Go there you wont regret it and you’ll think god you found him and this office.

Marc H. from San Francisco, CA (Source: Yelp)


Yesterday I got my bridge implant. I am so happy with the results. Listen when you see those commercials saying “one day” don’t believe them. Getting dental implants done correctly is a lengthy process, and each case is singular. Dr Karkar led me through the process with a kind and gentle hand. He is a lovely man, and an artist at what he does. Everyone that works there is wonderful. After the month’s long process I feel like I got to know all of them. Thank you Dental Angels!

G. from San Francisco, CA (Source: Yelp)


I came to Dental Angels when on of my front veneers popped off the day after the first Covid lock down in March 2019. My, then, regular dentist was only doing emergency work and didn’t know if he was going to continue his practice with Covid here and his retirement looming. We’d used the veneers as a short term solution to a structurally necessary crown, so this info meant looking for a new dentist and orthodontist who was taking new patients immediately, with a great track record, and be willing to take it on during the earliest days of Covid. Dental Angels answered that call and I could not be happier. From the warm welcomes from whomever when you open the door, especially Angelina, to Lupita’s gentle and exacting skills and to Dr. Karkar’s and Dr. Merejo’s knowledge, insight, and individualized guidance, working with Dental Angels has been a phenomenally positive experience. I have always felt fully understood, educated, and involved in each part of the process, which along with the overall soothing environment has made the dentist days closer to spa days. I cannot speak more highly of this team. The office is inviting, calming, and full of beautiful and vibrant art that is delightful for the eyes and enhanced by careful lighting. Pro-tips: Take a bit of CBD, cue up a couple of podcasts or a great playlist, keep the good sounds in your left ear, leave your right ear open so you can hear directions clearly and…relax. You are in fantastic hands.

Caitlin James (Source: Google)


No matter where I move in the world, every six months I will be here. It is a clean, well designed facility, with a kind and friendly staff. The doctor is gentle, detailed and informative. He walks you through every step of the process. No guilt trips for bad behavior, just guiding words of advice and friendly reminders.

Julie J. from Manhattan, New York, NY (Source: Yelp)


From the moment I walked in everyone treated me with great respect. I fear the dentist sometimes because they have the habit of making me feel bad for my teeth, but not these doctors. They handled my teeth with such great care, and after, I feel more confident than ever. Highly recommend!

Martin W. from San Francisco, CA (Source: Yelp)


I’ve gotten my wisdom teeth extracted here in late August and can’t even describe how happy I am to have chosen Dental Angels. I actually found them on Yelp and got an appointment within a week. My wisdom teeth weren’t impacted – I just wanted them out cause they had a cavity and when they first came out they pushed the rest of my teeth a bit around and since I’m considering aligners right now I wanted then out first. Both of them came out in 1 piece. Within 10 minutes. No pain, no swelling at all. I’m still amazed how flawless this entire process was. So happy to have found Dental Angels!

Moy V. from San Francisco, CA (Source: Yelp)


I was searching for a new dentist in my neighboorhood when I bumped into Dental Angel’s on Yelp and I am glad I did. I was able to book a same-day appointment due to a cancelation. The practice is amazingly clean with modern state of the art equipment. The staff was also equally amazing. From the front desk assistant to the dental hygienist to the actual doctor. I received great service with kindness and a smile. This will definitely be my long term dentist from now on. Highly recommended.

Allison D. from San Francisco, CA (Source: Yelp)


I truly cannot say enough good things about this place. They treat every patient like family, and use state-of-the-art equipment and use the latest technology. Dr. Karkar and his team are brilliant, and he uses techniques to where I don’t feel any pain at all when my teeth are extracted. Everyone is also so refreshingly sweet and friendly; the dentists, the assistants, the receptionists.. everyone gives a warm friendly attitude and goes the extra mile to make sure you’re comfortable. I honestly think I really did find the best dentist in the Bay Area based on my several dental visits.


We are a full service dental practice that goes well beyond basic cleanings and checkups to offer all general and cosmetic procedures within one location. We provide a full range of dental care from routine preventive care to cosmetic makeovers. Our team of dentists offer everything from exams and cleanings, crowns, and root canals to veneers, whitening, and orthodontics. We have a state-of-the-art facility that utilizes cutting edge technology and techniques. We specialize in implant dentistry and love helping patients replace missing teeth with a safe, effective, and long-term solution. We are a one-stop shop for dentistry, which means we also offer CBCT imaging and Invisalign orthodontic treatment. ABOUT US Committed to providing our patients with the highest quality of care possible We are on a mission to provide exceptional dental care using the latest technology and techniques. Our practice offers a wide range of dental services, with an emphasis on cosmetic and implant dentistry. Dr. Issa George Karkar, managing partner, has been a leading lecturer for new innovative dental techniques for the past 28 years. Dr. Karkar holds a DDS from the University of California at San Francisco and a BS in Biochemistry and Computer Science from the University of San Francisco. He is founder of The Institute of Digital Dentistry in San Francisco, served seven years as a Board Member for the Academy of Computerized Dentistry, is currently on the Board of Directors of the Italian Academy of Computerized Dentistry, held the position of Associate Clinical Professor in the Implantology Program of the Alameda County Medical Center as well as Associate Clinical Professor at the Branemark International Academy. He is on a mission to deliver the highest quality of care in the most comfortable, highest tech environment for every patient. He never compromises his quality of care.