Jessica Desouza Dentistry
Jessica Desouza, DDS:
Practice Profile Page


Jessica Desouza Dentistry
Jessica Desouza, DDS
New York, NY (Midtown East)













A list of major dental treatments which I offer my patients:

Dental cleaning

White fillings


Inlays & onlays


Clear aligners

Porcelain veneers

Teeth whitening

Dentures & partials

Root canal treatment

Tooth extraction

TMJ treatment

Dental implants


Offers Even28 at-home™? No

Offers Even28 at-dentist™? No

Offers Invisalign®? Yes


Monday: 9:00 am to 6:00 pm

Tuesday: 9:00 am to 6:00 pm

Wednesday: 9:00 am to 6:00 pm

Thursday: 9:00 am to 6:00 pm

Friday: 9:00 am to 6:00 pm

Saturday: Closed

Sunday: Closed





Check out what some of our happy patients are saying about us:

Monte B. from Manhattan, New York, NY (Source: Yelp)


A great dentist! Dr. DeSouza and the office staff are fantastic and always make sure I am as comfortable as someone can be at a dentist office. She has always offered different options and made recommendations about my dental routine that have been very helpful. And while she does offer suggestions, you never feel like you are being lectured to or other procedures are being pushed on you. If you’re looking for a dentist, I would highly recommend Dr. DeSouza.

Alisha Mess (Source: Google)


Dr. Jessica deSouza is an amazing dentist, and I feel so lucky to have found her. She’s very welcoming and informative and has certainly improved my oral health. She and her staff are very gentle and care deeply about their patients. I definitely recommend having her as your dentist; you’re in excellent hands.

Sandy C. from New York, NY (Source: Yelp)


Dr. DeSouza has been my Dentist for the past 6 years and I have always felt confident in her work and professionalism. I recently had to see her for a check up and cleaning and as always she was quick to see me. She found an infection and was efficient in the next steps. She was honest about what had to be done to take care of it. What makes having her as my Dentist even better is her kindness, cleanliness, and thoroughness that is hard to find nowadays. And, to top it all off, her staff is friendly and willing to work with different insurance plans. Definitely a Dentist anyone would like to have for a lifetime!

Natalie L. from San Francisco, CA (Source: Yelp)


About 5 yrs old years ago I had really bad situation going on with my gums. I started look around for a dentist that could help me.  Doctor deSouza was recommended to me. Doctor  deSouza went out her way to help me and I was very pleased with her.  She explained everything thoroughly and helped me a lot.  Thanks.

Yolanda M. from West New York, NJ (Source: Yelp)


Dr. DeSouza is by far the best dentist I’ve ever had in NYC. For a while I’d been looking for a dentist I could trust or at the very least liked. A friend recommended Dr. DeSouza to me and I am soooo grateful! She is the consummate professional, gentle, thorough, and provides excellent service. She is also very warm and friendly with a genuine interest in making sure that her patients understand the importance of maintaining good oral health. An added bonus was that she has an awesome office staff as well. It was an all around amazing experience! Never thought I’d say that about a dental visit!

Jongnic B. from Salinas, CA (Source: Yelp)


Jessica is my go to dentist when I am in NYC!  She is not only extremely competent, but has a wonderful demeanor.  I went to her with my mouth a mess; several cavities, receding gums, and a tooth on the verge of falling out of my mouth.  She saved and rebuilt that tooth, took care of all the cavities and strengthened my gums.  My mouth has never been in better shape. I live in LA now, but all the dentists I have seen since here marvel at her work.

T Williams (Source: Google)


Professional and quality service! Dr. deSouza does a thorough job with regular cleanings and took good care of my dental concerns that I shared when I switched to her from another dentist. I am also pleased with her great follow-up care, in person and via telehealth during the pandemic. She is knowledgeable about current industry practices and was able to give me treatment options and explain the differences. It’s evident that she enjoys what she does and I highly recommend her for your dental needs.

Karleen Leveille (Source: Google)


Dr. DeSouza did an excellent job with my teeth cleaning. She was extremely gentle and thorough. Her friendly demeanor took away any anxiety I had going to a dentist. My smile is 1000% better which is important because I work in the entertainment industry. She is a dentist with a great personable energy.

Lannia Small (Source: Google)


Dr. deSouza is one of the best dentists I’ve been to in Manhattan. She is incredibly knowledgeable, conciencious and honest. Her cleanings are always a pleasant experience, no pain and my teeth are gleaming for weeks. She also places a lot of importance on general oral health and prevention. She’s recommended several products to help strengthen my teeth and reduce plaque buildup between cleanings. I highly recommend her!

Jongnic Bontemps (Source: Google)


Jessica is an artist! She cares deeply about her patients and her work. She knows that the best billboard is your smile and she takes pride in creating the best billboards in New York City. A few years ago she rebuilt a severely eroded tooth. I’ve since moved to Los Angeles and every dentist I see out here marvels at her work. 7 years and it’s still holding up with no pain or signs of erosion. And it looks great too! That’s art. Two things I miss about NYC. It’s energy and Jessica Desouza DDS.

Lucinda Rosa (Source: Google)


If you are looking for an honest and gentle dentist, Dr. Jessica DeSouza is the dentist you want to see. She was able to fit me in late hours and I didn’t have to miss work SUPER convenient ! She even accommodated me on a Sunday for my follow up, how amazing is that? My experience was excellent, she really took her time to get my dental concerns addressed. This experience has now allowed me to become more comfortable in seeing a dentist. I am going to recommend her to everyone I know.

Suzy E. from Manhattan, NY (Source: Yelp)


Suzy E. from Manhattan, NYDr. DeSouza is thorough, patient, and highly professional. I recently relocated and was looking for a dentist who was reliable, professional, and a wonderful resource on how to maintain good oral hygiene. During a recent cleaning, Dr. DeSouza provided feedback on specific products I could use to improve gum care. She provided samples and insisted that I follow-up if I had further questions or concerns. Overall, Dr. DeSouza is personable and time-efficient. There was great adherence to timed appointments, routine call reminders, and consistent follow-up. The practice is wonderful and highly recommended.

Karleen L. from Springfield Gardens, NY (Source: Yelp)


I had gone to a number of dentist for basic cleanings and typically by the time I leave, my teeth are sore. Also, there is usually a wait to see a doctor and the doctors treat me like a file instead of a patient. However, whenever I visit Dr. DeSouza, I never have to wait, my teeth ALWAYS SPARKLES when I leave and she remembers me every time I see her. Her staff is also incredible too. They keep the office upbeat and clean! What I also appreciate is if I call the office and have a question about pain or discomfort, Dr. DeSouza is always willing to answer my questions.

Dione B. from South Ozone Park, NY (Source: Yelp)


Dr. deSouza and her staff are very friendly and attentive. As soon as you enter the office, you are made to feel welcomed and relaxed (which is much needed when getting certain procedures done). The first time I visited Dr. deSouza’s office was after developing a severe case of TMJ. I had gone to my own Dentist about the issue, but he didn’t offer much assistance. Dr DeSouza was the complete opposite, showing extreme concern and looking into several approaches for dissolving the pain and correcting the issues. She took the time to communicate possible causes and solutions and practiced extreme patience while listening to my responses. Since then she continues to periodically follow-up with me. Will definitely continue going to her!

Carmen Del Valle (Source: Google)


Dr. deSouza was amazing. Ahead of my visit, I had a bit of anxiety since my last experience with a different dentist was not great. Dr. deSouza and her team walked me through what I was to expect and regularly checked in to make sure I was comfortable throughout my cleaning. She was incredibly gentle but effective and solidified my trust in her. I left feeling great and actually look forward to my next cleaning.

Ivette Casanova (Source: Google)


I was looking for an experienced, thorough and friendly dentist and I do not need to look further! I’m so happy to have met Dr. de Souza. She is kind and compassionate about her care for her patients. I had a wonderful experience. She’s gentle, committed to the dental health of her patients and offers wide range of services. It was my first time at her dental office and I must say it was a great experience!!
Best dentist ever!! Ivette C.

Lauren R. from Manhattan, NY (Source: Yelp)


Dr. deSouza and her staff are incredible! I have been plagued with teeth problems my entire life. When I first visited Dr. deSouza, I was in need of two root canals after having three done that previous year. She and her staff, especially Erica, were kind, patient, thorough, and professional. After Dr. deSouza completed my root canals, I was pain free and have not had any issues since my first visit three years ago. Dr. deSouza and her staff have incredible attention to detail, making sure that you and your teeth receive the best care. It’s important to note they do not push any unnecessary dental work onto you, unlike the other NYC dentists I’ve used. They simply do what is best for you and your teeth. Since my first visit three years ago, I have recommended dr. deSouza to many people I know, and now most of my office has switched to her practice. Everyone loves her!

Alourdes Elmine (Source: Google)


Dr De Souza has been my dentist for about 7 years now. I met her at another practice. She did fillings for me on my back teeth and she had to give me an injection all the way in the back of my mouth, and those shots are usually painful. She has the hands of an artist, I didn’t even feel the shot and the fillings were beautiful. She match the color of my teeth as well as the shape. She didn’t shave it down to nothing. I have never had any issues with those fillings and her cleanings are amazing as well. I would recommend Dr Desouza to all my family and friends because she is a smart, talented, warm and caring dentist. I love her ❤️

Yolanda Moore (Source: Google)


Dr. DeSouza is the best dentist I’ve had in NYC! A friend recommended her to me and I am sooo very grateful. She was very gentle, and thorough with a kind, pleasant personality which made me feel very safe under her care. I really appreciated that she walked me through what to expect during my procedure. In speaking with her, it was evident that she really cares about teaching her patients how to maintain good oral health. My experience was excellent…. I’d give more stars if I could!

Jordan Welte (Source: Google)


Dr. deSouza is the best dentist I’ve had. I’ve not had great experiences in the past with dentists so I am always hesitant when choosing a dentist. Dr. deSouza takes time to explain what she is doing as she goes. She is patient, kind, and gentle in her work. I highly recommend her to anyone looking for dental work.