Lifesmile Dental Care
Blake Setien, DDS:
Practice Profile Page


Lifesmile Dental Care
Blake Setien, DDS
Hazelwood, MO













A list of major dental treatments which I offer my patients:

Dental cleaning

White fillings


Inlays & onlays


Clear aligners

Porcelain veneers

Teeth whitening

Dentures & partials

Root canal treatment

Tooth extraction

TMJ treatment

Dental implants


Offers Even28 at-home™? No

Offers Even28 at-dentist™? No

Offers Invisalign®? Yes


Monday: 8:00 am to 5:00 pm

Tuesday: 8:00 am to 5:00 pm

Wednesday: 8:00 am to 6:00 pm

Thursday: 10:00 am to 8:00 pm

Friday: Closed

Saturday: Closed

Sunday: Closed





Check out what some of our happy patients are saying about us:

Richelle T. from Florissant, MO (Source: Yelp)


Dr. Blake and Sarah working on my tooth today. What a Great Doctor and what a great job he did. He made me feel comfortable and calm. The needle didn’t hurt at all , not even a pinch and that’s the part I typically panic about. My new crown emerged from their magic crown making machine and I’m ready to go. . Thank you Dr. Blake and Sarah. I appreciate you both. . For an awesome experience, Lifesmiles is the place to go.

Bianca Hill (Source: Google)


This was hands down the best dental care I’ve ever received from such a loving and caring dental office! I was shocked at how sweet and knowledgeable the rep was who answered the phone when I made our appointments. You could feel her positive energy and contagious laugh through the phone. But I see her energy was matched by more great energy in office! Everyone from the front desk ladies, to the technicians, to the doctors, to the coordinators were amazing! I have never felt this comfortable anywhere and would recommend LifeSmiles Dental to everyone looking for a family or single dentist! They all even worked well with my two small children! I can not thank them all enough and we will never go anywhere else again!

Jeff Williams (Source: Facebook)


I love LifeSmile! Been going there for many years and always get the best service. My recent visits have been with Samantha and she’s terrific. Very detail oriented and always does great work. She also takes time to explain things and set my mind at ease. I wish more health care professionals had that human touch. Seems sadly lacking these days. Clone Samantha! The front desk team is also great. Warm and friendly and very professional.

Ashtersshadow8 (Source: Google)


I’ve been going here for years now and the staff is always pleasant and thorough. They never express a hint of judgement about the state of my teeth and always have recommendations on how to improve my dental cleaning. If you’re in the area and need dental work, please give them a try!

Alicia Cameron (Source: Google)


The staff assistants, management, and doctors have really went out of their way (actually, “above and beyond”) to make sure that I am satisfied with the extensive work that I have had done. My front upper crowns are so natural looking that an actual dentist did not realize that they were crowns upon visual inspection. If I ever have a problem they get me in right away for an exam. All of the dentists are caring and understanding. They care about your comfort during treatment and the quality of their work. I highly recommend them!

S W (Source: Google)


After having several horrible dental experiences at different establishment, it was such a relief to find LifeSmile Dental Care. The office itself is super clean and welcoming, and Dr. Blake and his staff are amazing – just so patient and kind. Their regular services are super affordable and appointments are easy to schedule without long wait times. I highly recommend this place to anyone seeking top level dental care.

Parvez Yusufji (Source: Google)


Every time I have been to LifeSmile, they have been excellent. I’ve had regular teeth cleanings and fillings from them. I almost never have to wait. If the appointment is for 8am, I’m in the chair by 8:01am. They communicate well about the services, perform the services well, and genuinely care. I’ve read about other people’s billing experiences, but I have never had a problem. Its always been clear when I owe and how much I owe.

Rita Clemons (Source: Google)


LifeSmile Dental was Tony the Tiger GRRRRREEEEEAAAAT!!!!! It was my son and daughter’s first time visiting. The staff was VERY professional, kind and courteous. From the young lady at the front desk to Kerri the New Patient Coordinator to the Dental Technician, Natalie (& Ashley) finally Dr. Blake, everyone was very, very humble and nice. They all smiled TOO! There were a few workers that passed us from time to time and they were equally as courteous as well. Thank you LifeSmile for making Evan’s first visit a very good one. One he hopefully, will not forget. I sure will not. Thank you for welcoming my Family and I to your facility.

Renee Whitley (Source: Google)


I want let the people out there that are looking for great dental care then look no further Life Smile Dental Care is the place for you. They are nice and friendly and very helpful. What I really like is two nights a week they stay open late so those of us who are working and do not want to take of work or use sick time then Life Smile is the place for you.

Ashli Walters (Source: Google)


100% recommend their services and would absolutely go back for any dental needs. From the moment I called about my son the staff went above and beyond. The got us in the same day because he is a seven year old in pain. They worked with us and even helped me with my nearly two year old daughter While I was attempting to attend to my son. My son was very difficult and they never once expressed frustration or became impatient. They were absolutely amazing. I am so thankful for such an amazing staff I feel if they hadn’t been so awesome I would have left there frustrated and embarrassed due to my sons difficult behavior but their professionalism and kindness made the terrible experience less terrible. Best office dental or otherwise I have ever visited.

Brian Miller (Source: Facebook)


The staff and dr is wonderful. I’ve had several bad experiences with Aspen Dental and I told them about the problems I had with Aspen dental, the moment I walked in the door the staff was welcoming and thanked me for choosing Life Smile. What a wonderful change from Aspen. My entire visit was excellent and they explain everything to you and make sure you understand everything. I’m recommending them to all my friends

Kayla Yates (Source: Google)


I never went to a dental office when I was a kid because my parents had bad experiences and never wanted to put us through what they went through. Coming to LifeSmile Dental Care was nerve wracking but they put all my worries to ease. Between the ladies at the front desk, the assistance, to the doctors.. I am happy I finally found my home dental office. 10/10 all the way.

LizzBeth Gassel Perkins (Source: Facebook)


I had to go in for a super bad toothache yesterday. Not only did they work to accommodate my schedule that day, they also took extra care to explain all my options. I am incredibly nervous about the dentist, but through calming techniques and being super supportive and caring, the dentist and tech were able to pull my tooth without sedation, gas, medication, or a nervous breakdown from me. While I have the normal amount of pain you would expect today, I went to work just 13 hours after the procedure! I would guess this is due in part to being given excellent instructions on how to care for myself after leaving. Really—all around greatness. They really care about you as a person and not just as a patient!

Shirley London-miles (Source: Facebook)


I love the service and the staff are very caring, they make me feel like I am a priority, Kelley was the dental assistant that was working with me, very personable and knowledgeable put me completely at ease, my dentist was a young lady I had met for the first time, but I hope I get her from now own. Thank You LifeSmile.

C.J. new (Source: Google)


I have been going to LifeSmile Dental Care for decades, started back in the 1980’s.I have had nothing but excellent care all those years.I am a retired military person, and could get my dental care at a military base, but I have stuck with the best, all the doctors and tech’s at LifeSmile Dental, and will stay with them as long as they are in operation

Autumn Incuba (Source: Facebook)


Have been going to Life Smile since the 1980’s. Miss Dr. Brown but all of the dentists and staff have always treated me well and I would not trust anyone else with my dental health!! Also first time at the Kirkwood Office yesterday, beautiful office and equally great staff there! Thank you.

Stephanie Davenport-Hatcher (Source: Facebook)


I have never liked going to the dentist but everyone at Life Smile made me super comfortable and feel less stress. Everyone there is so nice and compassionate. I would recommend them to everyone. The best part is you can not even feel the first shot that Dr. Brent gives you. I don’t know how he does it but it is awesome.

Cliff Fields (Source: Facebook)


I’m so happy that I can smile again. I have been dealing with a discolor tooth for years. My former dentist really wasn’t making me happy about it.I even try to pull it out myself. Lol . My wife told me about Life Smile. I’m so glad she did. I went there just to see what can be done for my tooth and left with a smile. I will be back again and the staff was awesome �����

Layshona Moffatt (Source: Google)


Wonderful and organized staff! An absolute kudos to Michelle who went above and beyond to assist and better help me understand my Treatment Plan; explained the cost of my services detail-by-detail. My biggest concern going to any dental office or getting any cosmetic or dental services has always been receiving service and not being aware of what I’m being charged, what my insurance covers, and any underlying fees before hand due to lack of communication. However, with Doctor Abbey Smith performing a thorough examination of my needs and Michelle being by her side to take notes, both were able to prioritize my needs of service so I can properly plan and budget accordingly.

Sherrell D. from Sherrell D. Saint Louis, MO (Source: Yelp)


My experience with this dental office for me can’t be expressed in words but I’ll try. Prior to going to Lifesmile I was terrified of the dentist resulting in me getting a lot of teeth pulled and having a horrible mouth. I finally couldn’t take it anymore and decided to use them. On my first visit we did xrays and actually came up with a plan for my mouth. Believe it or not we are sticking with the plan and with each visit my confidence is building and I’m not ashamed to have a conversation with people. I still have a ways to go but I’m excited. All the employees are very nice and understanding!

Judy Sisak (Source: Google)


I had never been there before and they were very nice people! The doctor I got to see today, she told me everything that I needed to know! And the young lady who was taking care of my ex rays thank you I know that I couldn’t get my mouth to open and she was very understanding! All and all I was very impressed by how much they care for their clients

Nakeisha finney (Source: Google)


I had the Pleasure of having Tori as my dental hygienist. Tori is the Sweetest and most heart felt person ever. My goodness. I had some troubles and she never gave up on me. When something didn’t work she found a different instrument and keep trying until we found what worked for me. Tori never became frustrated with me. She talked me through the entire procedure. Tori even gave me breathing exercises to get me through it. I’m big on Customer Service not only because it’s what my job consist of but because it’s who I am. I needed her right by my side. Her positive energy is simply overwhelming. I’m so very Grateful to have met Tori. She’s someone that I will never forget. Lifestyle your Lucky to have Tori. Whatever awards you give out she deserves them and so much more. A raise wouldn’t hurt either. Very Happy Customer

Deborah Ross (Source: Google)


I had a great experience with my checkup! The staff are so nice and caring! They always take time to explain any foreseen problems during my examines. I love how they are willing to work around your schedule to accommodate you!! Great job LifeSmile Dental Care!! Keep during what you do best – taking great care of our teeth/smile!!!

Brittany Tharp (Source: Google)


I have been a patient at LifeSmile since I was a little girl and have grown up with them. The entire staff is wonderful and always greets me with a smile and asks about my family. I really feel as if they care about me and I enjoy visiting them twice a year for my regular visits. My husband now goes to them as well and we love it. We plan on being patients for a long time!

Anthony Brooks (Source: Google)


I must say that my experience at lifesmile dental care has been great, the staff there are some of the nicest people I’ve ever met in my life. From Dr.Blake to all the ladies in the office and examination room they all get high marks from me!!! My smile has improved greatly since day one, I always enjoy my appointments because the professionalism and friendliness of lifesmiles staff. My wife and kids also have been going there for years and i highly recommend lifesmile, on a scale of 1 to 10 I give them a 100 best dentist office I’ve ever gone to. Thx for all the great work you guys have done for my family much appreciated !!!! Happy Thanksgiving to everyone that work at Lifesmile Dental best dentist office ever !!!! HAPPY 2019 TO EVERYONE AT LIFESMILE. Happy MOTHER’S Day to all the ladies at lifesmile dental. I’ve only had great experiences at lifesmile dental, my wife got the visaline and it closed her gap, I give lifesmile a 10, the dentist, the office woman, the dental assistants all get a 10 plus from me, highly recommended i rank lifesmile dental as my favorite dental office of my adult life, thank you so much Dr Blake, Dr Heber and all the assistants and staff, also Dr Brent did a great job closing the gap in my wife’s front teeth.!!!! Thank you everyone at lifesmile Dental. Merry Christmas and Happy New Year to all the staff at Lifesmile Dental and a great 2020 you guys are the best !!!! Every experience I’ve had at lifesmile dental has always been a great one, thx again lifesmile dental. Thanks again to everyone at lifesmile 5 stars always !!!!!! Just had my 6 month cleaning 9/13/2021 Lifesmile Dental gets all 10’s from me, very professional great staff and facility highly recommended!!!

Chris Smith (Source: Google)


I trust LifeSmile employees and doctors with my family’s and my dental care. They treat me like family. I don’t feel like they judge me or preach to me. I know some places do. My husband and I love all the doctors and hygienists. The assistants are all knowledgeable and caring. Thank you to Dr Brent and Andrea for making my crown.

Sinetria Staples (Source: Facebook)


Today was my first visit to LifeSmile and it was amazing! Everyone in the office was so nice. I had my 3 month old with me and he was a little fussy which of course made me nervous and a little flustered. However, the ladies were so welcoming and understanding. Everyone came to visit with him while I had my work done. He spent the rest of the time laughing lol. Not only that but they were so informative with my dental work. Coming here was a great decision. Thank you ladies so much 

Brooke Freed (Source: Google)


Best dentist EVER. The staff, the dedication to their patients both in and out of office. I’ve never particularly had good experiences with dentists but being there is a genuine pleasure. Tv’s and comfy chairs. Gentle care. Couldn’t ask for a better dentist. Major shoutout to the receptionist at the kirkwood location, Rachel. She texted me back on a weekend to schedule an emergency visit… I don’t even respond to work texts on the weekend!!!! Amazing love these guys ❤️

Elizabeth Gassel Perkins (Source: Google)


I had to go in for a super bad toothache yesterday. Not only did they work to accommodate my schedule that day, they also took extra care to explain all my options. I am incredibly nervous about the dentist, but through calming techniques and being super supportive and caring, the dentist and tech were able to pull my tooth without sedation, gas, medication, or a nervous breakdown from me. While I have the normal amount of pain you would expect today, I went to work just 13 hours after the procedure! I would guess this is due in part to being given excellent instructions on how to care for myself after leaving. Really—all around greatness. They really care about you as a person and not just as a patient!

Cheryl Gerber (Source: Facebook)


I was VERY impressed with the entire staff who attended to me on my initial visit to this dental office. I had X-rays done of my entire mouth. Dr Blake Setien took his time with his exam, diagnosing a problem I have had for some time, that was missed by another dentist. Kayla ran numbers for me, informing me of my out of pocket amount after insurance. When making an appointment for cleaning my teeth, a canceled appointment was noted, I got in that very afternoon, saving me time and a trip back to the office. Natalie, the hygienist, was quick and competent. I would highly recommend this team of professionals for any dental needs.

Kevin Hilligoss (Source: Facebook)


Been a fan of LifeSmile Dental care for almost 25 years now. The staff is always very friendly and helpful. It’s nice to walk in and be helped by people like Sandy, Michelle, Natalie, and Meagan, and all the great staff there. The dentist have always taken great care of me from minor work and up to some major dental work which was needed. I recommend LifeSmile to all my family and friends.

Phyllis LovedbyGod Moore Hicks (Source: Facebook)


The service I received was great, that’s when you don’t mind going back to receive more services. The staff members are very friendly and make you feel comfortable the entire visit. If you don’t have dental care now I highly recommend LifeSmile Dental Care and I approve this message

Beverly Dotson (Source: Facebook)


Look-a-here people; I got myself into a dental crisis today and want to sincerely thank the staff and Ms Teresa for keeping this smile in tact and sweet! They got me in and out within 1 hour! Thank you! Faithful customer Beverly Dotson

Barbara Preston Reilley (Source: Facebook)


They took very good care of my daughter when she had her wisdom teeth removed. The aftercare was exceptional and the staff went above and beyond to make her comfortable and as a mom who was out of town at the time, it gave me great comfort.