Rene Der Gregorian Dentistry
Rene Der Gregorian, DMD:
Practice Profile Page


Rene Der Gregorian Dentisrty
Rene A. Der Gregorian, DMD
Pasadena, CA













A list of major dental treatments which I offer my patients:

Dental cleaning

White fillings


Inlays & onlays



Clear aligners

Porcelain veneers

Teeth whitening

Dentures & partials

Root canal treatment

Tooth extraction

Sedation dentistry

TMJ treatment

Dental implants


Offers Even28 at-home™? No

Offers Even28 at-dentist™? No

Offers Invisalign®? Yes


Monday: 9:30 am to 5:30 pm

Tuesday: 9:30 am to 2:30 pm

Wednesday: 9:30 am to 5:30 pm

Thursday: 9:30 am to 5:30 pm

Friday: Closed

Saturday: Closed

Sunday: Closed





Check out what some of our happy patients are saying about us:

Chelsea M. from Pasadena, CA (Source: Yelp)


I have to say… this is the BEST DENTIST I HAVE EVER BEEN TO! My husband and I suffer from extreme anxiety when it comes to anything dental. Jasmine is an amazing receptionist that has a very calming energy, we chat while my husband flipflop appointments. Farah is a warm, caring Dental Hygienist that is thorough :)! Dr. Der Gregorian is beyond exceptional. He is honest, gentle, and very good communicating! What an amazing experience! I would recommend this place to EVERYONE!

Jenny T. from La Puente, CA (Source: Yelp)


My husband and I are both patients of Dr. Gregorian.  He is one of the few honest dentists out there.   Unlike other dental offices out there, Dr. Gregorian told me his concerns with my teeth and suggested only necessary procedures.  I had four wisdom teeth and another dentist told me i had to remove ALL of them.  Dr. Gregorian, on the other hand, told me only ONE had to be taken care of.  He explained everything is detail and patiently answered all my questions before any treatment.  His office manager, Jasmine, is very friendly.  She called me a few times in the month following my root canal and crown procedure just to check and see if I was doing okay.   My husband recently had his teeth pulled out and Dr. Gregorian did a great job.  We both feel comfortable having him and his staff to take care of all our dental needs. The office looks like any other residential house.  It’s between a gas station and a auto repair shop.  The small driveway on the left of building will lead you to a parking lot in the back.  Street parking is nearly impossible but then again, I never had problem finding parking in the lot.   They are not opened everyday so it is best to call and schedule ahead before driving there.   Yes, we will recommend this office to our friends and family.

Crystal L. from Los Angeles, CA (Source: Yelp)


I was skeptical of this place because it was kinda at a weird location. Also if you are wondering yea, it is an actual house! I asked the dentist himself. Lol. However, once you go inside, it is really nicely decorated. The receptionist was super nice and sweet, very rare at dentists and doctor offices. My mom’s root canal was deemed unworkable by several regular dentists so we were referred to Dr. Rene. Dr. Rene was really, really awesome! My mom didn’t speak English and actually liked going to this dentist because he was attentive and he gave these little glasses to wear so she wasn’t blinded by the lights! No other dentist has done that for her. Her root canal was really tough, in fact Dr. Rene said he has never seen a tooth like that before haha. He worked so diligently on her tooth and asked constantly if my mom was ok. My mom has NO more pain after that! Also this place was farther from where we live and “less known” on yelp, but the price was actually cheaper than places near our home. It’s definitely worth the drive for the service and  customer service.

Joyce G. from West Covina, CA (Source: Yelp)


Dr. Der Gregorian is the best dentist. He is friendly and funny. I was skeptical since it is a far drive but I was wrong. He is very detailed. I had my root canal for the very first time. It didn’t hurt and didn’t feel a thing… It is right next to ARCO so I parked at the residential since the driveway is tight… Simply Fantastic and Awesome Dentist…. Love the friendly service…

Rachel P. from Pasadena, CA (Source: Yelp)


I rarely write reviews on yelp but I wanted to review Dr. Gregorian’s office specifically because I had such a pleasant experience there. The facility is clean and Dr. Gregorian and his team do an unbelievable job making sure your experience there is a great one! They are warm and professional and enjoyable to be around. I had a crown replaced and Dr. Gregorian and his dental assistant did an excellent, thorough job. It is so refreshing to find people taking pride in their work and in giving exceptional care to their patients! Highly recommend!

Rebecca R. from San Gabriel, CA (Source: Yelp)


Dr. Der Gregorian is phenomenal! Just got back from my appointment, mouth still numb, and couldn’t be happier I switched dentists. He made sure I was completely numb and frequently checked everything was great, which was truly great. He also made sure to explain everything in detail, things my other dentist left me wondering about. The end result so far feels perfect!

Sherry Y. from Los Angeles, CA (Source: Yelp)


Dr. Der Gregorian is an amazingly gentle and is a highly competent, caring dentist. I fell asleep getting a deep cleaning.  He took the time to show me my x-rays and educate me as to the condition of my teeth and what steps could be taken to better my teeth and correct a few issues. He completed a crown for me and I’m very happy with the my smile. I’m referring all my friends and would take my kids, but for the fact that he doesn’t see little ones. His dental assistant is awesome! She is definitely a wonderful person. I also received reminders about upcoming appointments from the front office, which is very helpful to me.  I was able to schedule and even reschedule my appointment without having to wait a year to see the dentist.

Becky L. from Los Angeles, CA (Source: Yelp)


I love this small, family run practice and feel very fortunate to have been referred to him through a co-worker. He has now been my dentist for the last 4 years and I have never felt more educated and taken care of by a dentist. I live in Los Feliz and wouldn’t even consider going to a closer dentist. He is well worth the drive and I highly recommend Dr. Der Gergorian if you are looking for a dentist.

Ash Ershadi (Source: Google)


Dr. Gregorian is one of the few dentists I’ve been to that puts my best interest first and does not try upselling me treatment I don’t need. He is extremely kind hearted and takes his time explaining different treatments to you. Would highly recommend!

Istante P. from Pasadena, CA (Source: Yelp)


This is the best dental office I have ever been to! Honest Doctor, amazing staff, experienced, clean, trustworthy and overall the best dental experience I have ever came across. I would not go anywhere other than Dr. Rene’s office. There was no waiting time, but even then if i did have to wait I wouldn’t complain. The waiting room feels like a living room and the office is so beautiful and tidy it is like a second home to me. I would highly recommend this office to any one who is in need of a caring, passionate, honest, professional, overall amazing dentist!!

Susana G. M. from Los Angeles, CA (Source: Yelp)


I concur. The Dr. is awesome! I had heard of his awesome skills as a dentist. Not to mention his work ethic and professionalism. I can barely wait for my next check up. The experience was awesome. The receptionist and the entire staff was very professional. I have recommended friends and family. I live close to USC, the trip was well worth it. Kuddos!

Ivy S. from San Diego, CA (Source: Yelp)


I want my old dentist back!! Rene Der Gregorian is the best dentist I’ve ever been to. When I moved to San Diego, I’d still go to him for all my dental needs. He is so kind and has a conservative approach to treating your dental needs. I love his wife Jasmine too. She works the front desk and is also a favorite human. I moved to Texas a couple years ago and miss my dentist so much. I’ve had a terrible time finding someone new. My experience here in Houston has prompted me to write a review for Rene as he really is someone special. I can’t recommend him enough. And I miss him!!!!

Ana M. from Alhambra, Los Angeles, CA (Source: Yelp)


What a great experience! Dr. Gregorian and his staff were friendly and professional. Prior to scheduling an appointment in this office, I spoke with Jasmin who was very knowledgeable about all my insurance questions and details about procedures that I was sure I needed. No long waits or over booking. My husband and I are very pleased and will continue to show off our smile.

Kacey C. from Newbury Park, CA (Source: Yelp)


I was a little skeptical to come here at first, because it’s such a long drive for me. I was referred to Dr. Gregorian by my dentist, because I was having some extreme pain after a temporary crown was put in a few weeks ago since he thought I might need a root canal. His office is kind of in a random place, right next to an Arco gas station. It looks like an old yellow house, but has a crazy amount of dentist/advertisement signs all over it. Parking is down a very narrow alley….there is a small lot behind the building. What you see outside is different from what you see inside. The inside looks more professional and clean. Staff wass sooo nice. The receptionist is very nice and easy going over the phone and in person. Flora, the dental assistant, was equally as nice. Dr. Gregorian was awesome! He has a very friendly smile. He’s also just a caring person in general. He’s careful about asking you to make sure you are comfortable and understand what he is about to do before he does it. Him and his staff just seem genuinely thoughtful. Very cautious about the fact that I was in a lot of pain…gave me little glasses to wear while they did some filing on my tooth. Just in general, they seem to take everything into account while treating you and try to make sure you are very comfortable. In the end of appointment, I ended up not getting a root canal…and I appreciate that Dr. Gregorian didn’t push it on me and tried other things to make sure my pain wasnt caused by something else (which I think it is). Also, very reasonably priced! Would definitely come back again.

Anne S. from Glendale, CA (Source: Yelp)


I was referred to Dr. Rene Der Gregorian from my cousin. I recently moved to the area from Wisconsin, so I have been going through the pain of setting up all my doctors – body, eye, teeth… you get the idea! It’s exhausting. This place made it so easy to talk insurance and book an appointment. I will be the first to admit that my dentist-going habits have been, well, lacking these past few years. I was worried that a new dentist would be swift to judge and lecture. I was THRILLED that Dr. Rene Der Gregorian was not that way at all. This was above and beyond the best dentist experience I have ever had. Thank you!!

Barb S. from Los Angeles, CA (Source: Yelp)


I wasn’t blessed with good teeth; and consequently have had good, bad and horrific dental experiences. This office is just amazing. The entire staff goes out of their way to make it actually pleasant! Dr. Der Gregorian is a very gifted Dr. he’s extremely gentle, kind and compassionate.  His prices are very reasonable as welI. BONUS!!! I drive all the way from Brentwood ~ but it’s totally worth it. Very highly recommend him – absolutely wonderful!

Mauricio V. from West Covina, CA (Source: Yelp)


The best word to describe this dentist is AMAZING!!! Not only is he extremely professional, but he has the hands of a brain surgeon. I was able to fall asleep as he worked on me. His office is very neat and they always take me in on time! Yazmin at the front desk is always extremely helpful and kind. I highly recommend this dentist to every family out there. Oh and one more very important thing… Dr Gregorian will never perform any unnecessary work on you. He is a very honest man!!


This Dental Practice is owned and operated by Dr. Rene A. Der Gregorian, who is a veteran of the U.S. Army Dental Corp. Dr. Der Gregorian, D.M.D. was opened with the intention to help provide quality and honest dental care. The amount of extensive training that Dr. Der Gregorian received in endodontics while serving as an active duty military dentist has made Dr. Der Gregorian well known among his patients, colleagues, and community as the go to dentist for root canal therapy and dental emergencies. He takes pride in being able to provide each patient the information, time, and attention they deserve by seeing only one patient at a time and refraining from overbooking treatment appointments. He is strives on earning your trust. Dr. Der Gregorian earned his Doctor of Medical Dentistry Degree from Case Western Reserve University School of Dental Medicine in Cleveland, Ohio. Immediately following his graduation from Dental School, Dr. Der Gregorian entered into active military service with the U.S. Army at Fort Bliss, El Paso, Texas. It was there that he had the honor to work with other dental specialists that awakened his passion for endodontics and emergency dentistry. Dr. Der Gregorian was given dental privileges at William Beaumont Army Medical Center, where he was occasionally on call to treat traumatic dental emergencies. After two years of service, he was promoted to Officer in Charge of the Biggs Air Field Dental Clinic where he was responsible for the oral healt of approximately five thousand active duty soldiers. For his service he recieved the Army Commendation Medal among others. After completing his active duty service, Dr. Der Gregorian returned home to Southern California, where he began his own private practice. Aside from working at his dental practice, he also continues to serve his fellow servicemembers as a dental contractor for the Department of Defense. On his sparetime, Dr. Der Gregorian enjoys Barbeques with his wife, children, and friends.